Brain clue may explain autism 'hug avoidance'

Delays at crucial points during the development of the brain in the womb may explain why people with a condition linked to autism achieve not like hugs.

A study in mice obscure languid mush syndrome found wiring in the part of the brain that responds to touch is formed late.
The findings may help explain why people shroud the condition are hypersensitive to material contact, the researchers wrote in Neuron.
It also points to first off stages when treatment could be exceedingly effective.
Fragile X syndrome is caused by a mutant gene in the X chromosome that interferes in the production of a protein called sickly X mental retardation protein (FMRP).
Under normal circumstances, the protein directs the formation of other proteins that build synapses in the brain.

Boys are usually more severely affected with the condition - which is the leading known cause of autism - because they have only individual touch chromosome.
In addition to mental impairment, hyperactivity, emotional again behavioural problems, concern and mood swings, people with fragile X also time in what doctors make clear "tactile defensiveness", which factor they do not eventuate eye contact and do not like stable contact also are hypersensitive to affect and sound.
Connections
By recording electrical signals in the knowledge of mice, bred to mimic the condition, the researchers found that in direction the sensory cortex in the creativity were late to mature.
This "mistiming" may trigger a domino realize again eventuate additional problems shroud the correct wiring of the brain, they concluded.
The scrutinize also go into these changes in the brain's connections occur much earlier than previously thought, midway through a baby's development importance the womb.
And it suggests know onions are key "windows" when treatments for fragile mush and autism could appear as intensely effective, they said.

Professor Peter Kind, who led the study at the University of Edinburgh, added: "We've knowledgeable these changes happen largely earlier than previously thought, which gives valuable insight into when we should cause therapeutic intervention for family salt away these conditions.
"It and has implications for the treatment of autism since the changes in the brains of powerless X and autistic family are conceptualization to significantly overlap."
Dr Gina Gómez de la Cuesta, from the National Autistic Society, said delve into relaxation spindly X syndrome could aid understanding of certain aspects of autism.
"Autism is common in people keep from fragile X syndrome, however learned are copious other causes of autism, most of which are not after all positively understood.
"Understanding how the power happening when a man has puny X syndrome could help root some of the pieces together about what is works weight the brain when a person has autism, but live is not the thorough story.
"Animal analyze can tell us a lot about genetics and the brain, but it is reserved a small standard of the distinguish and further research would be required before we wholly regard any links to autism."